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The combination of ipratropium and albuterol optimizes pulmonary function reversibility testing in patients with COPD.
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Inhalation by nebulization of albuterol-ipratropium combination (Dey combination) is superior to either agent alone in the treatment of chronic obstructive pulmonary disease.
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The absolute FEV1 values at 360 min after Ipraterol treatment was still higher than the baseline values.
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In acute bronchoconstriction, the combination of a b 2 adrenergic agonist and ipratropium is more effective than either agent alone and more effective than simply giving more b 2 adrenergic agonist (Bryant, 1985; Bryant and Rogers, 1992).
The inhaler contains a dose indicator.
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In the 6-mo open-label extension, there were fewer exacerbations and less need for reliever medication with adjustable-dose budesonide and formoterol.
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Tashkin DP, Donohue JF, Mahler DA, Huang H, Goodwin E, Schaefer K, Hanrahan JP, Andrews WT: Effects of arformoterol twice daily, tiotropium once daily, and their combination in patients with COPD.
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Higher doses of albuterol should be used with caution in patients with cardiac disease, arrhythmias, or hypertension.
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The doses and strengths of the available dosage forms are expressed in terms of pirbuterol (not the acetate salt).
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These inhalers consist of a pressurized canister containing medication that fits into a boot-shaped plastic mouthpiece.
ACTH test in asthmatic children treated with inhaled beclomethasone or theophylline.
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Levalbuterol is substantially excreted by the kidney, and the risk of toxic reactions may be greater in patients with impaired renal function.
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The enrolment of patients who have had an exacerbation within the six weeks prior to planned study entry has to be postponed.
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When compared with albuterol, 200 μg, in 24 patients with COPD, ipratropium, 40 μg, plus fenoterol, 100 μg, produced a similar maximal increase in FEV 1 (32 versus 31% with albuterol) and a similar decrease in specific airway resistance (24 versus 21% with albuterol) ().
Spacers are useful for all patients, especially young children and older adults (see picture B).
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When rabbits were given oral albuterol at doses corresponding to 2315 times the maximum inhalation dose for a 50-kg human, cranioschisis occurred in 37% of their fetuses.
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Yawn BP, Colice GL, Hodder R: Practical aspects of inhaler use in the management of chronic obstructive pulmonary disease in the primary care setting.
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As for the inhaler, it's typically one dose daily for maintenance and several more doses taken at fifteen seconds interval for severe bouts of obstructive lung disease.
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Patients using salmeterol for exercise-induced bronchospasm should not use additional doses for twelve hours after each prophylactic administration.
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Breathe-in as deeply as possible, pressing the base of the container firmly at the same time, this releases 1 metered dose.
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